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J. Funct. Biomater. 2014, 5(1), 15-26; doi:10.3390/jfb5010015

Application of Sub-Micrometer Vibrations to Mitigate Bacterial Adhesion

*  and *
Department of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA
* Authors to whom correspondence should be addressed.
Received: 14 January 2014 / Revised: 26 February 2014 / Accepted: 28 February 2014 / Published: 11 March 2014
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As a prominent concern regarding implantable devices, eliminating the threat of opportunistic bacterial infection represents a significant benefit to both patient health and device function. Current treatment options focus on chemical approaches to negate bacterial adhesion, however, these methods are in some ways limited. The scope of this study was to assess the efficacy of a novel means of modulating bacterial adhesion through the application of vibrations using magnetoelastic materials. Magnetoelastic materials possess unique magnetostrictive property that can convert a magnetic field stimulus into a mechanical deformation. In vitro experiments demonstrated that vibrational loads generated by the magnetoelastic materials significantly reduced the number of adherent bacteria on samples exposed to Escherichia coli, Staphylococcus epidermidis and Staphylococcus aureus suspensions. These experiments demonstrate that vibrational loads from magnetoelastic materials can be used as a post-deployment activated means to deter bacterial adhesion and device infection.
Keywords: antifouling; magnetoelastic materials; sub-micron vibrations antifouling; magnetoelastic materials; sub-micron vibrations
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Paces, W.R.; Holmes, H.R.; Vlaisavljevich, E.; Snyder, K.L.; Tan, E.L.; Rajachar, R.M.; Ong, K.G. Application of Sub-Micrometer Vibrations to Mitigate Bacterial Adhesion. J. Funct. Biomater. 2014, 5, 15-26.

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