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J. Funct. Biomater. 2011, 2(2), 31-38; doi:10.3390/jfb2020031

Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride

* ,
Departamento de Química Física II, Facultad de Farmacia, UCM, 28040 Madrid, Spain
* Author to whom correspondence should be addressed.
Received: 8 April 2011 / Revised: 16 May 2011 / Accepted: 30 May 2011 / Published: 31 May 2011
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The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly increased the cement FST and the addition of 10% SrCl2 decreased the cement tensile strength. Further, cement weight loss was shown to be increased by cement modification with SrCl2. The combination of ionic substitution and the degradability of brushite cements would constitute a system for the local delivery of strontium ions in the treatment of osteoporosis.
Keywords: Brushite; calcium phosphate cement; strontium; glycolic acid Brushite; calcium phosphate cement; strontium; glycolic acid
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Alkhraisat, M.H.; Rueda, C.; López Cabarcos, E. Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride. J. Funct. Biomater. 2011, 2, 31-38.

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J. Funct. Biomater. EISSN 2079-4983 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert