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Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
Departamento de Química Física II, Facultad de Farmacia, UCM, 28040 Madrid, Spain
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Received: 8 April 2011; in revised form: 16 May 2011 / Accepted: 30 May 2011 / Published: 31 May 2011
Abstract: The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly increased the cement FST and the addition of 10% SrCl2 decreased the cement tensile strength. Further, cement weight loss was shown to be increased by cement modification with SrCl2. The combination of ionic substitution and the degradability of brushite cements would constitute a system for the local delivery of strontium ions in the treatment of osteoporosis.
Keywords: Brushite; calcium phosphate cement; strontium; glycolic acid
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Alkhraisat, M.H.; Rueda, C.; López Cabarcos, E. Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride. J. Funct. Biomater. 2011, 2, 31-38.
Alkhraisat MH, Rueda C, López Cabarcos E. Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride. Journal of Functional Biomaterials. 2011; 2(2):31-38.
Alkhraisat, Mohammad H.; Rueda, Carmen; López Cabarcos, Enrique. 2011. "Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride." J. Funct. Biomater. 2, no. 2: 31-38.