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J. Clin. Med. 2015, 4(4), 593-613; doi:10.3390/jcm4040593

Biological Treatments in Atopic Dermatitis

Department of Dermatology, Hospital Universitario de La Princesa, Diego de León 62, Madrid 28006, Spain
These authors contributed equally to this work.
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Author to whom correspondence should be addressed.
Academic Editors: Sebastien Barbarot and Kim Thomas
Received: 31 January 2015 / Revised: 3 March 2015 / Accepted: 13 March 2015 / Published: 3 April 2015
(This article belongs to the Special Issue Epidemiology and Treatment of Atopic Eczema)
View Full-Text   |   Download PDF [192 KB, uploaded 3 April 2015]

Abstract

Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases that affect both children and adults with a prevalence of 30% and 10%, respectively. Even though most of patients respond satisfactory to topical anti-inflammatory drugs, about 10% require one or more systemic treatments to achieve good control of their illness. The progressive and increasingly detailed knowledge in the immunopathogenesis of AD has allowed research on new therapeutic targets with very promising results in the field of biological therapy. In this article, we will review the different biological treatments with a focus on novel drugs. Their mechanism of action, current status and results from clinical trials and observational studies will be specified. View Full-Text
Keywords: atopic eczema; atopic dermatitis; pathogenesis; biologics; antibody therapy atopic eczema; atopic dermatitis; pathogenesis; biologics; antibody therapy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Montes-Torres, A.; Llamas-Velasco, M.; Pérez-Plaza, A.; Solano-López, G.; Sánchez-Pérez, J. Biological Treatments in Atopic Dermatitis. J. Clin. Med. 2015, 4, 593-613.

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