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Brain Sci. 2017, 7(4), 39; doi:10.3390/brainsci7040039

Is Decompressive Surgery for Cervical Spondylotic Myelopathy Effective in Patients Suffering from Concomitant Multiple Sclerosis or Parkinson’s Disease?

1
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
2
Cleveland Clinic Center for Spine Health, Cleveland Clinic, 9500 Euclid Ave, S-80, Cleveland, OH 44195, USA
3
Department of Neurological Surgery, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Evanthia Bernitsas
Received: 24 February 2017 / Revised: 29 March 2017 / Accepted: 6 April 2017 / Published: 10 April 2017
(This article belongs to the Special Issue Pathophysiology and Imaging Diagnosis of Demyelinating Disorders)
View Full-Text   |   Download PDF [201 KB, uploaded 10 April 2017]

Abstract

A subset of patients with a demyelinating disease suffer from concurrent cervical spondylotic myelopathy, both of which evince similar symptomatology. Differentiating the cause of these symptoms is challenging, and little research has been done on patients with coexisting diseases. This review explores the current literature on the appropriate surgical management of patients with concurrent multiple sclerosis (MS) and cervical spondylotic myelopathy (CSM), and those with both Parkinson’s disease (PD) and CSM. MS and CSM patients may benefit from surgery to reduce pain and radiculopathy. Surgical management in PD and CSM patients has shown minimal quality-of-life improvement. Future studies are needed to better characterize demyelinating disease patients with concurrent disease and to determine ideal medical or surgical treatment. View Full-Text
Keywords: demyelinating disease; multiple sclerosis (MS); cervical spondylotic myelopathy (CSM); Parkinson’s disease (PD); demyelination; myelopathy; outcomes demyelinating disease; multiple sclerosis (MS); cervical spondylotic myelopathy (CSM); Parkinson’s disease (PD); demyelination; myelopathy; outcomes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Purvis, T.E.; Lubelski, D.; Mroz, T.E. Is Decompressive Surgery for Cervical Spondylotic Myelopathy Effective in Patients Suffering from Concomitant Multiple Sclerosis or Parkinson’s Disease? Brain Sci. 2017, 7, 39.

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