Antimicrobial Effect of Titanium Hydroxyapatite in Denture Base Resin
AbstractIn the current study, we investigated the antimicrobial effect of titanium hydroxyapatite (TiHA), a photo-oxidizing organic material, in denture base resin on single-species biofilms formed by laboratory bacteria and on multispecies biofilms formed by bacteria from the human saliva. Although TiHA reportedly restricts the growth of planktonic bacteria upon ultraviolet A (UVA) irradiation, the antimicrobial effect of TiHA on bacterial biofilms remains to be elucidated. Resin specimens were prepared by adding TiHA to polymethyl methacrylate-based, denture base resin. The specimens were incubated with biofilm-forming Streptococcus sanguinis, Actinomyces naeslundii, Staphylococcus aureus, Escherichia coli, or bacteria from the human saliva obtained from volunteers. After UVA irradiation, the colony-forming units (CFUs) from the biofilms formed on the specimens were determined. CFU numbers for S. sanguinis, A. naeslundii, and S. aureus that formed biofilms on TiHA-containing specimens were significantly lower than those formed on specimens without TiHA. TiHA did not reduce the CFUs of biofilm-forming E. coli. In all cases, CFU numbers in the biofilms formed on TiHA-containing specimens by the salivary bacteria were significantly reduced. In addition, neither a 56 h UVA irradiation nor a 28 d soaking in water diminished the antibacterial effect of TiHA. TiHA in denture base resin exerts an antimicrobial effect on single-species bacterial biofilms and biofilms formed by a wide variety of bacteria from human saliva. View Full-Text
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Sato, W.; Yoshida, Y.; Komasa, S.; Hasegawa, Y.; Okazaki, J. Antimicrobial Effect of Titanium Hydroxyapatite in Denture Base Resin. Appl. Sci. 2018, 8, 963.
Sato W, Yoshida Y, Komasa S, Hasegawa Y, Okazaki J. Antimicrobial Effect of Titanium Hydroxyapatite in Denture Base Resin. Applied Sciences. 2018; 8(6):963.Chicago/Turabian Style
Sato, Wataru; Yoshida, Yasuo; Komasa, Satoshi; Hasegawa, Yoshiaki; Okazaki, Joji. 2018. "Antimicrobial Effect of Titanium Hydroxyapatite in Denture Base Resin." Appl. Sci. 8, no. 6: 963.
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