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Appl. Sci. 2014, 4(3), 402-443; doi:10.3390/app4030402

Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress

1
SUPA, Department of Physics, University of Strathclyde, Glasgow G40NG, Scotland, UK
2
Department of Physics, Faculty of Science, University of Selcuk, Konya 42031, Turkey
3
Faculty of Physics, Ludwig Maximilians University, Am Coulombwall 1, 85748 Garching, Germany
4
Kansai Photon Science Institute, Japan Atomic Energy Agency, 8-1-7 Umemidai, Kizugawa, Kyoto 619-0215, Japan
5
Radiation Oncology Department, Fox Chase Cancer Center, 333 Cottman Ave., Philadelphia, PA 19111, USA
*
Author to whom correspondence should be addressed.
Received: 18 June 2014 / Revised: 1 August 2014 / Accepted: 4 August 2014 / Published: 19 September 2014
(This article belongs to the Special Issue Casting Light on Cancer Therapy)

Abstract

It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumors. It has an innate ability to irradiate tumors with greater doses and spatial selectivity compared with electron and photon therapy and, hence, is a tissue sparing procedure. For more than twenty years, powerful lasers have generated high energy beams of protons and heavy ions and it has, therefore, frequently been speculated that lasers could be used as an alternative to radiofrequency (RF) accelerators to produce the particle beams necessary for cancer therapy. The present paper reviews the progress made towards laser driven hadron cancer therapy and what has still to be accomplished to realize its inherent enormous potential. View Full-Text
Keywords: proton radiotherapy; accelerators; high power lasers; laser acceleration; laser driven radiation therapy; laser desorption ionization; laser assisted classification of healthy and cancerous tissue; laser medical application centres proton radiotherapy; accelerators; high power lasers; laser acceleration; laser driven radiation therapy; laser desorption ionization; laser assisted classification of healthy and cancerous tissue; laser medical application centres
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Ledingham, K.W.D.; Bolton, P.R.; Shikazono, N.; Ma, C.-M.C. Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress. Appl. Sci. 2014, 4, 402-443.

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