Acute Administration of Caffeine: The Effect on Motor Coordination, Higher Brain Cognitive Functions, and the Social Behavior of BLC57 Mice
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals
2.2. Tests
2.2.1. Rotarod (RR)
2.2.2. Elevated Plus Maze Test (EPM)
2.2.3. Morris Water Maze Test (MWM)
2.2.4. Three-Chambers Social Apparatus (Crawley’s Sociability and Preference for Social Novelty Test) (3C)
3. Statistical Analysis
4. Results
4.1. Rotarod Test: Ac MD Displayed Better Motor Coordination than the Other Groups
4.2. Improved Performance Displayed by Ac MD Group in Morris Water Maze Test
4.3. Increased Anxiety in Caffeine-Treated Mice
4.4. Lack of Sociability and Preference for Social Novelty in Caffeine-Treated Mice
5. Discussion and Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Almosawi, S.; Baksh, H.; Qareeballa, A.; Falamarzi, F.; Alsaleh, B.; Alrabaani, M.; Alkalbani, A.; Mahdi, S.; Kamal, A. Acute Administration of Caffeine: The Effect on Motor Coordination, Higher Brain Cognitive Functions, and the Social Behavior of BLC57 Mice. Behav. Sci. 2018, 8, 65. https://doi.org/10.3390/bs8080065
Almosawi S, Baksh H, Qareeballa A, Falamarzi F, Alsaleh B, Alrabaani M, Alkalbani A, Mahdi S, Kamal A. Acute Administration of Caffeine: The Effect on Motor Coordination, Higher Brain Cognitive Functions, and the Social Behavior of BLC57 Mice. Behavioral Sciences. 2018; 8(8):65. https://doi.org/10.3390/bs8080065
Chicago/Turabian StyleAlmosawi, Sayed, Hasan Baksh, Abdulrahman Qareeballa, Faisal Falamarzi, Bano Alsaleh, Mallak Alrabaani, Ali Alkalbani, Sadiq Mahdi, and Amer Kamal. 2018. "Acute Administration of Caffeine: The Effect on Motor Coordination, Higher Brain Cognitive Functions, and the Social Behavior of BLC57 Mice" Behavioral Sciences 8, no. 8: 65. https://doi.org/10.3390/bs8080065