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Metals 2016, 6(1), 3;

Biodegradable Behaviors of Ultrafine-Grained ZE41A Magnesium Alloy in DMEM Solution

College of Mechanics and Materials, Hohai University, Nanjing 210098, China
Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology, Nanjing 226000, China
Author to whom correspondence should be addressed.
Academic Editors: Vineet V. Joshi and Alan Meier
Received: 10 October 2015 / Revised: 6 December 2015 / Accepted: 17 December 2015 / Published: 23 December 2015
(This article belongs to the Special Issue Oxidation of Metals)
View Full-Text   |   Download PDF [975 KB, uploaded 23 December 2015]   |  


The main limitation to the clinical application of magnesium alloys is their too-fast degradation rate in the physiological environment. Bio-corrosion behaviors of the ZE41A magnesium alloy processed by multi-pass equal channel angular pressing (ECAP) were investigated in Dulbecco's Modified Eagle Medium (DMEM) solution, in order to tailor the effect of grain ultrafining on the biodegradation rate of the alloy implant. Hydrogen evolution tests indicated that a large number of ECAP passes decreased the stable corrosion rate of the alloy after the initial incubation period. Potentiodynamic polarization curves showed that more ECAP passes made the corrosion potential nobler and the corrosion tendency lower. Corroded surfaces of the ECAPed alloy indicated a higher resistance toward localized corrosion due to the homogeneous redistribution of broken second phases on the ultrafine-grained Mg matrix. It suggests that grain ultrafining can decrease the biodegradable rate of the magnesium alloy-containing rare-earth elements and tailor the lifetime of the biodegradable material. View Full-Text
Keywords: magnesium alloy; biodegradation; ECAP; grain refinement; bio-corrosion magnesium alloy; biodegradation; ECAP; grain refinement; bio-corrosion

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Jiang, J.; Zhang, F.; Ma, A.; Song, D.; Chen, J.; Liu, H.; Qiang, M. Biodegradable Behaviors of Ultrafine-Grained ZE41A Magnesium Alloy in DMEM Solution. Metals 2016, 6, 3.

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