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Lubricants 2015, 3(2), 394-412; doi:10.3390/lubricants3020394

The Synovial Lining and Synovial Fluid Properties after Joint Arthroplasty

Vernon Luck Sr. M.D. Orthopaedic Research Center, Orthopaedic Institute for Children/UCLA, Los Angeles, CA 90007, USA
Departments of Pathology, and Orthopaedic Surgery, UCLA Santa Monica/Orthopaedic Hospital, Santa Monica, CA 90404, USA
Author to whom correspondence should be addressed.
Academic Editors: J. Philippe Kretzer and Amir Kamali
Received: 18 February 2015 / Revised: 4 May 2015 / Accepted: 5 May 2015 / Published: 18 May 2015
(This article belongs to the Special Issue Tribological Performance of Artificial Joints)
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The lubrication of the cartilaginous structures in human joints is provided by a fluid from a specialized layer of cells at the surface of a delicate tissue called the synovial lining. Little is known about the characteristics of the fluids produced after a joint arthroplasty procedure. A literature review was carried out to identify papers that characterized the synovial lining and the synovial fluids formed after total hip or knee arthroplasty. Five papers about synovial lining histology and six papers about the lubricating properties of the fluids were identified. The cells making up the re-formed synovial lining, as well as the lining of interface membranes, were similar to the typical Type A and B synoviocytes of normal joints. The synovial fluids around joint replacement devices were typically lower in viscosity than pre-arthroplasty fluids but the protein concentration and phospholipid concentrations tended to be comparable, suggesting that the lining tissue function was preserved after arthroplasty. The widespread, long-term success of joint arthroplasty suggests that the lubricant formed from implanted joint synovium is adequate for good clinical performance in the majority of joints. The role the fluid plays in component wear or failure is a topic for future study. View Full-Text
Keywords: synovial lining; synovial fluid; lubrication; histomorphological characterization; arthroplasty; implant; systematic review synovial lining; synovial fluid; lubrication; histomorphological characterization; arthroplasty; implant; systematic review

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Kung, M.S.; Markantonis, J.; Nelson, S.D.; Campbell, P. The Synovial Lining and Synovial Fluid Properties after Joint Arthroplasty. Lubricants 2015, 3, 394-412.

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