Next Article in Journal
Introducing Interesting Images
Next Article in Special Issue
Hybrid Imaging for Patient-Specific Dosimetry in Radionuclide Therapy
Previous Article in Journal / Special Issue
In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous 18F-FDG-PET and Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect
Article Menu

Export Article

Open AccessInteresting Images
Diagnostics 2015, 5(3), 290-293; doi:10.3390/diagnostics5030290

Brown Tumors Due to Primary Hyperparathyroidism in a Patient with Parathyroid Carcinoma Mimicking Skeletal Metastases on 18F-FDG PET/CT

Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9—PET 3982, DK-2100 Copenhagen, Denmark
*
Author to whom correspondence should be addressed.
Academic Editor: Andreas Kjaer
Received: 23 June 2015 / Revised: 6 July 2015 / Accepted: 6 July 2015 / Published: 9 July 2015
(This article belongs to the Collection Hybrid Imaging in Medicine)
View Full-Text   |   Download PDF [2919 KB, uploaded 9 July 2015]   |  

Abstract

Parathyroid carcinoma only represents <1% of all cases of primary hyperparathyroidism (PHPT). Even rare, chronic PHPT may lead to excessive osteoclast activity, and the increased resorption leads to destruction of cortical bone and formation of fibrous cysts with deposits of hemosiderin—so-called brown tumors. These benign, osteolytic lesions may demonstrate FDG-avidity on 18F-FDG PET/CT, and as such are misinterpreted as skeletal metastases. Regression of the lesions may occur following successful treatment. We present a case demonstrating the diagnostic work-up and follow-up of a patient with PHPT due to parathyroid carcinoma and with presence of brown tumors on 18F-FDG PET/CT, visualizing the possible role of this imaging modality in the evaluation of treatment response in these patients. View Full-Text
Keywords: brown tumors; parathyroid carcinoma; FDG PET; primary hyperparathyroidism brown tumors; parathyroid carcinoma; FDG PET; primary hyperparathyroidism
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Andersen, K.F.; Albrecht-Beste, E. Brown Tumors Due to Primary Hyperparathyroidism in a Patient with Parathyroid Carcinoma Mimicking Skeletal Metastases on 18F-FDG PET/CT. Diagnostics 2015, 5, 290-293.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Diagnostics EISSN 2075-4418 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top