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Diagnostics 2015, 5(2), 272-286; doi:10.3390/diagnostics5020272

Unintended Consequences of not Specifying Exclusionary Illnesses for Systemic Exertion Intolerance Disease

Center for Community Research, DePaul University, Chicago, IL 60614, USA
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Academic Editor: Andreas Kjaer
Received: 25 March 2015 / Revised: 10 June 2015 / Accepted: 16 June 2015 / Published: 23 June 2015
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Abstract

The Institute of Medicine recently proposed a new case definition for chronic fatigue syndrome (CFS), as well as a new name, Systemic Exertion Intolerance Disease (SEID). Contrary to the Fukuda et al.’s CFS case definition, there are few exclusionary illnesses specified for this new SEID case definition. The current study explored this decision regarding exclusionary illnesses using the SEID criteria with four distinct data sets involving patients who had been identified as having CFS, as well as healthy controls, community controls, and other illness groups. The findings indicate that many individuals from major depressive disorder illness groups as well as other medical illnesses were categorized as having SEID. The past CFS Fukuda et al. prevalence rate in a community based sample of 0.42 increased by 2.8 times with the new SEID criteria. The consequences for this broadening of the case definition are discussed. View Full-Text
Keywords: Myalgic Encephalomyelitis; chronic fatigue syndrome; systemic exertion intolerance disease; case definitions Myalgic Encephalomyelitis; chronic fatigue syndrome; systemic exertion intolerance disease; case definitions
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Jason, L.A.; Sunnquist, M.; Kot, B.; Brown, A. Unintended Consequences of not Specifying Exclusionary Illnesses for Systemic Exertion Intolerance Disease. Diagnostics 2015, 5, 272-286.

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