What Froze the Genetic Code?
AbstractThe frozen accident theory of the Genetic Code was a proposal by Francis Crick that attempted to explain the universal nature of the Genetic Code and the fact that it only contains information for twenty amino acids. Fifty years later, it is clear that variations to the universal Genetic Code exist in nature and that translation is not limited to twenty amino acids. However, given the astonishing diversity of life on earth, and the extended evolutionary time that has taken place since the emergence of the extant Genetic Code, the idea that the translation apparatus is for the most part immobile remains true. Here, we will offer a potential explanation to the reason why the code has remained mostly stable for over three billion years, and discuss some of the mechanisms that allow species to overcome the intrinsic functional limitations of the protein synthesis machinery. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Ribas de Pouplana, L.; Torres, A.G.; Rafels-Ybern, À. What Froze the Genetic Code? Life 2017, 7, 14.
Ribas de Pouplana L, Torres AG, Rafels-Ybern À. What Froze the Genetic Code? Life. 2017; 7(2):14.Chicago/Turabian Style
Ribas de Pouplana, Lluís; Torres, Adrian G.; Rafels-Ybern, Àlbert. 2017. "What Froze the Genetic Code?" Life 7, no. 2: 14.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.