tRNA Core Hypothesis for the Transition from the RNA World to the Ribonucleoprotein World
AbstractHerein we present the tRNA core hypothesis, which emphasizes the central role of tRNAs molecules in the origin and evolution of fundamental biological processes. tRNAs gave origin to the first genes (mRNA) and the peptidyl transferase center (rRNA), proto-tRNAs were at the core of a proto-translation system, and the anticodon and operational codes then arose in tRNAs molecules. Metabolic pathways emerged from evolutionary pressures of the decoding systems. The transitions from the RNA world to the ribonucleoprotein world to modern biological systems were driven by three kinds of tRNAs transitions, to wit, tRNAs leading to both mRNA and rRNA. View Full-Text
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de Farias, S.T.; Rêgo, T.G.; José, M.V. tRNA Core Hypothesis for the Transition from the RNA World to the Ribonucleoprotein World. Life 2016, 6, 15.
de Farias ST, Rêgo TG, José MV. tRNA Core Hypothesis for the Transition from the RNA World to the Ribonucleoprotein World. Life. 2016; 6(2):15.Chicago/Turabian Style
de Farias, Savio T.; Rêgo, Thais G.; José, Marco V. 2016. "tRNA Core Hypothesis for the Transition from the RNA World to the Ribonucleoprotein World." Life 6, no. 2: 15.
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