Cordyceps militaris Inhibited Angiotensin-Converting Enzyme through Molecular Interaction between Cordycepin and ACE C-Domain
Abstract
:1. Introduction
2. Materials and Methods
2.1. Preparation of Cordyceps militaris Ethanolic Extract
2.2. UHPLC-FD Analysis
2.3. Measurement of ACE Inhibitory Activity
2.4. Molecular Docking between ACE C-Domain and Cordycepin
2.5. Statistical Analysis
3. Results
3.1. UHPLC Analysis
3.2. Kinetics of ACE Inhibition
3.3. Molecular Docking between ACE C-Domain and Cordycepin
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Acknowledgments
Conflicts of Interest
References
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Valdez-Solana, M.A.; Corral-Guerrero, I.A.; Téllez-Valencia, A.; Avitia-Domínguez, C.; Meza-Velázquez, J.A.; de Casa, A.G.; Sierra-Campos, E. Cordyceps militaris Inhibited Angiotensin-Converting Enzyme through Molecular Interaction between Cordycepin and ACE C-Domain. Life 2022, 12, 1450. https://doi.org/10.3390/life12091450
Valdez-Solana MA, Corral-Guerrero IA, Téllez-Valencia A, Avitia-Domínguez C, Meza-Velázquez JA, de Casa AG, Sierra-Campos E. Cordyceps militaris Inhibited Angiotensin-Converting Enzyme through Molecular Interaction between Cordycepin and ACE C-Domain. Life. 2022; 12(9):1450. https://doi.org/10.3390/life12091450
Chicago/Turabian StyleValdez-Solana, Mónica A., Iván A. Corral-Guerrero, Alfredo Téllez-Valencia, Claudia Avitia-Domínguez, Jorge A. Meza-Velázquez, Atahualpa Guzmán de Casa, and Erick Sierra-Campos. 2022. "Cordyceps militaris Inhibited Angiotensin-Converting Enzyme through Molecular Interaction between Cordycepin and ACE C-Domain" Life 12, no. 9: 1450. https://doi.org/10.3390/life12091450