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Genes 2016, 7(11), 98; doi:10.3390/genes7110098

Gene Therapy: A Paradigm Shift in Dentistry

1
Department of Oral Biology, Bahria University Medical and Dental College, Karachi 75260, Pakistan
2
Department of Biomedical Engineering, College of Engineering, King Faisal University, Al-Hofuf 31982, Saudia Arabia
3
Department of Restorative Dentistry, College of Dentistry, Taibah University, Madina Munawwarrah 41311, Saudi Arabia
*
Author to whom correspondence should be addressed.
Academic Editor: Michael Barry
Received: 28 July 2016 / Revised: 16 October 2016 / Accepted: 3 November 2016 / Published: 10 November 2016
(This article belongs to the Special Issue Gene Therapy)
View Full-Text   |   Download PDF [1605 KB, uploaded 10 November 2016]   |  

Abstract

Gene therapy holds a promising future for bridging the gap between the disciplines of medicine and clinical dentistry. The dynamic treatment approaches of gene therapy have been advancing by leaps and bounds. They are transforming the conventional approaches into more precise and preventive ones that may limit the need of using drugs and surgery. The oral cavity is one of the most accessible areas for the clinical applications of gene therapy for various oral tissues. The idea of genetic engineering has become more exciting due to its advantages over other treatment modalities. For instance, the body is neither subjected to an invasive surgery nor deep wounds, nor is it susceptible to systemic effects of drugs. The aim of this article is to review the gene therapy applications in the field of dentistry. In addition, therapeutic benefits in terms of treatment of diseases, minimal invasion and maximum outcomes have been discussed. View Full-Text
Keywords: gene therapy; pain; cancer; DNA vaccination; bone repair; tooth repair; orthodontic tooth movement gene therapy; pain; cancer; DNA vaccination; bone repair; tooth repair; orthodontic tooth movement
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Siddique, N.; Raza, H.; Ahmed, S.; Khurshid, Z.; Zafar, M.S. Gene Therapy: A Paradigm Shift in Dentistry. Genes 2016, 7, 98.

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