Next Article in Journal
Impacts of Fertilization Type on Soil Microbial Biomass and Nutrient Availability in Two Agroecological Zones of Ghana
Previous Article in Journal
Characterisation of Faba Bean (Vicia faba L.) Transcriptome Using RNA-Seq: Sequencing, De Novo Assembly, Annotation, and Expression Analysis
Article Menu
Issue 3 (September) cover image

Export Article

Open AccessArticle
Agronomy 2017, 7(3), 54; doi:10.3390/agronomy7030054

Combination of Lactic Acid-Based Deep Eutectic Solvents (DES) with β-Cyclodextrin: Performance Screening Using Ultrasound-Assisted Extraction of Polyphenols from Selected Native Greek Medicinal Plants

1
School of Environment, University of the Aegean, Mitr. Ioakim Street, Myrina, Lemnos 81400, Greece
2
Aegean Organics Ltd., Aghios Dimitrios, Lemnos 81400, Greece
*
Author to whom correspondence should be addressed.
Academic Editor: Peter Langridge
Received: 23 June 2017 / Revised: 6 August 2017 / Accepted: 9 August 2017 / Published: 14 August 2017
View Full-Text   |   Download PDF [3312 KB, uploaded 14 August 2017]   |  

Abstract

A series of novel l-lactic acid-based deep eutectic solvents (DES) were tested for polyphenol extraction performance, using organically grown, native Greek medicinal plants. The extractions were ultrasonically-assisted and the effect of the addition of β-cyclodextrin (β-CD) as extraction booster was also tested, at a concentration of 1.5% (w/v). The estimation of total polyphenol yield (YTP) suggested that DES composed of l-lactic acid and nicotinamide and l-lactic acid and l-alanine, both at a molar ratio of 7:1, are promising solvents giving significantly higher yields compared with 60% (v/v) aqueous ethanol and water. However, when β-CD was combined with DES comprised of l-lactic acid and ammonium acetate (molar ratio 7:1), the extraction yields obtained in some instances were equal of even higher. The pattern was not consistent when the yield in total flavonoids (YTFn) was considered, indicating water, 60% (v/v) aqueous ethanol and l-lactic acid:sodium acetate (molar ratio 7:1) to be the most efficient solvents. In this case, the effect of β-CD was of rather lower magnitude. The examination of the antioxidant activity of the extracts generated showed that there is a close correlation mainly with their concentration in total polyphenols. View Full-Text
Keywords: antioxidants; β-cyclodextrin; deep eutectic solvents; medicinal plants; polyphenols; ultrasound-assisted extraction antioxidants; β-cyclodextrin; deep eutectic solvents; medicinal plants; polyphenols; ultrasound-assisted extraction
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Georgantzi, C.; Lioliou, A.-E.; Paterakis, N.; Makris, D.P. Combination of Lactic Acid-Based Deep Eutectic Solvents (DES) with β-Cyclodextrin: Performance Screening Using Ultrasound-Assisted Extraction of Polyphenols from Selected Native Greek Medicinal Plants. Agronomy 2017, 7, 54.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Agronomy EISSN 2073-4395 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top