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Polymers 2016, 8(11), 398; doi:10.3390/polym8110398

Physical and Mechanical Evaluation of Silicone-Based Double-Layer Adhesive Patch Intended for Keloids and Scar Treatment Therapy

1
Department of Pharmaceutical Technology, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Medical University of Gdansk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland
2
Department of Physical Chemistry, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Medical University of Gdansk, Al. Gen. Hallera 107, 80-416 Gdańsk, Poland
3
Institute of Experimental Physics, Faculty of Mathematics, Physics and Informatics, University of Gdansk, Wita Stwosza 57, 80-308 Gdańsk, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Antonio Pizzi
Received: 14 September 2016 / Revised: 26 October 2016 / Accepted: 9 November 2016 / Published: 22 November 2016
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Abstract

Growing interest in silicone elastomers for pharmaceutical purposes is due to both their beneficial material effect for scar treatment and their potential as drug carriers. Regarding their morphological structure, silicone polymers possess unique properties, which enable a wide range of applicability possibilities. The present study focused on developing a double-layer adhesive silicone film (DLASil) by evaluating its physical and mechanical properties, morphology, and stability. DLASil suitability for treatment of scars and keloids was evaluated by measurement of tensile strength, elasticity modulus, and elongation. The results indicated that mechanical and physical properties of the developed product were satisfying. View Full-Text
Keywords: adhesive silicone skin dressing; scar treatment; mechanical properties; tensile strength; morphology adhesive silicone skin dressing; scar treatment; mechanical properties; tensile strength; morphology
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Mikolaszek, B.; Jamrógiewicz, M.; Mojsiewicz-Pieńkowska, K.; Żebrowska, M.; Sznitowska, M.; Strankowska, J. Physical and Mechanical Evaluation of Silicone-Based Double-Layer Adhesive Patch Intended for Keloids and Scar Treatment Therapy. Polymers 2016, 8, 398.

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