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Coarse-Grained Models for Protein-Cell Membrane Interactions
AbstractThe physiological properties of biological soft matter are the product of collective interactions, which span many time and length scales. Recent computational modeling efforts have helped illuminate experiments that characterize the ways in which proteins modulate membrane physics. Linking these models across time and length scales in a multiscale model explains how atomistic information propagates to larger scales. This paper reviews continuum modeling and coarse-grained molecular dynamics methods, which connect atomistic simulations and single-molecule experiments with the observed microscopic or mesoscale properties of soft-matter systems essential to our understanding of cells, particularly those involved in sculpting and remodeling cell membranes.
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Bradley, R.; Radhakrishnan, R. Coarse-Grained Models for Protein-Cell Membrane Interactions. Polymers 2013, 5, 890-936.View more citation formats
Bradley R, Radhakrishnan R. Coarse-Grained Models for Protein-Cell Membrane Interactions. Polymers. 2013; 5(3):890-936.Chicago/Turabian Style
Bradley, Ryan; Radhakrishnan, Ravi. 2013. "Coarse-Grained Models for Protein-Cell Membrane Interactions." Polymers 5, no. 3: 890-936.