Next Article in Journal
Next Article in Special Issue
Previous Article in Journal
Previous Article in Special Issue
Catalysts 2013, 3(4), 794-810; doi:10.3390/catal3040794
Review

Palladium-Catalyzed Intermolecular Oxidative Amination of Alkenes with Amines, Using Molecular Oxygen as Terminal Oxidant

*  and
Received: 25 July 2013; in revised form: 29 September 2013 / Accepted: 8 October 2013 / Published: 16 October 2013
(This article belongs to the Special Issue Palladium Catalysts for Cross-Coupling Reaction)
View Full-Text   |   Download PDF [719 KB, uploaded 16 October 2013]
Abstract: In this review, we summarize recent progress from our group with regard to Pd-catalyzed oxidative amination of alkenes with amines. Intermolecular oxidative amination of alkenes with secondary anilines was induced using a palladium-complex catalyst combined with molybdovanadophosphate as a co-catalyst under dioxygen, leading to allylic amines and enamines in good yields with high selectivities. The reaction proceeded efficiently, using molecular oxygen as the terminal oxidant. In addition, palladium-catalyzed oxidative amination of alkenes with anilines as primary amines was achieved using molecular oxygen as the sole oxidant, producing (Z)-N-alkenyl-substituted anilines in high yields.
Keywords: amination; enamine; allylic amine; molybdovanadophosphate; oxidative coupling; alkenes amination; enamine; allylic amine; molybdovanadophosphate; oxidative coupling; alkenes
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Obora, Y.; Ishii, Y. Palladium-Catalyzed Intermolecular Oxidative Amination of Alkenes with Amines, Using Molecular Oxygen as Terminal Oxidant. Catalysts 2013, 3, 794-810.

AMA Style

Obora Y, Ishii Y. Palladium-Catalyzed Intermolecular Oxidative Amination of Alkenes with Amines, Using Molecular Oxygen as Terminal Oxidant. Catalysts. 2013; 3(4):794-810.

Chicago/Turabian Style

Obora, Yasushi; Ishii, Yasutaka. 2013. "Palladium-Catalyzed Intermolecular Oxidative Amination of Alkenes with Amines, Using Molecular Oxygen as Terminal Oxidant." Catalysts 3, no. 4: 794-810.


Catalysts EISSN 2073-4344 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert