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Cancers 2015, 7(4), 2318-2329; doi:10.3390/cancers7040893

Optimizing Management of Patients with Adult T Cell Leukemia-Lymphoma

Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD 21204, USA
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Jonas Cicenas
Received: 17 September 2015 / Revised: 5 November 2015 / Accepted: 17 November 2015 / Published: 25 November 2015
(This article belongs to the Special Issue Lymphoma)
View Full-Text   |   Download PDF [617 KB, uploaded 25 November 2015]   |  


Adult T cell leukemia-lymphoma is a rare disease with a high mortality rate, and is challenging for the clinician. Early allogeneic stem cell transplant can confer durable remission. As novel therapeutic agents become available to treat T cell malignancies, it is increasingly important that medical oncologists, hematologists, and hematopathologists recognize and accurately diagnose adult T cell leukemia-lymphoma. There is no uniform standard of treatment of adult T cell leukemia-lymphoma, and clinical trials remain critical to improving outcomes. Here we present one management approach based on the recent advances in treatment for adult T cell leukemia-lymphoma patients. View Full-Text
Keywords: adult T cell leukemia-lymphoma; ATL; ATLL; allogeneic; HTLV-1; transplantation; chemotherapy; antiviral treatment adult T cell leukemia-lymphoma; ATL; ATLL; allogeneic; HTLV-1; transplantation; chemotherapy; antiviral treatment

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Yared, J.A.; Kimball, A.S. Optimizing Management of Patients with Adult T Cell Leukemia-Lymphoma. Cancers 2015, 7, 2318-2329.

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