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Cancers 2014, 6(3), 1705-1726; doi:10.3390/cancers6031705

Human Papillomavirus in Head and Neck Cancer

Laboratory of Virology, "L. Spallanzani" National Institute for Infectious Diseases, Via Portuense, 292, 00149 Rome, Italy
Received: 30 May 2014 / Revised: 6 August 2014 / Accepted: 7 August 2014 / Published: 18 August 2014
(This article belongs to the Special Issue DNA Viruses in Human Cancer)
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Abstract

Human papillomavirus (HPV) is currently considered to be a major etiologic factor, in addition to tobacco and alcohol, for oropharyngeal cancer (OPC) development. HPV positive OPCs are epidemiologically distinct from HPV negative ones, and are characterized by younger age at onset, male predominance, and strong association with sexual behaviors. HPV16 is the most prevalent types in oral cavity cancer (OCC), moreover the prevalence of beta, and gamma HPV types is higher than that of alpha HPV in oral cavity. View Full-Text
Keywords: human papillomavirus; oral; cancer human papillomavirus; oral; cancer
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Garbuglia, A.R. Human Papillomavirus in Head and Neck Cancer. Cancers 2014, 6, 1705-1726.

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