Abstract: Advanced intra-abdominal desmoids tumors present with severe symptoms, complications or rapid growth, which lead to adverse outcomes. Our aim was to evaluate the treatment and outcome of patients with advanced intra-abdominal desmoids tumors, and develop guidelines for surgical management of these patients. We reviewed the clinical courses of 21 adult patients with advanced stage intra-abdominal desmoid tumors who presented to an intestinal rehabilitation and transplantation program. Patients with massive intestinal resection presented in two groups. The first group had a short small intestinal remnant after resection ( < 60 cm). These patients were poor rehabilitation candidates and eventually met criteria for transplant. The second had longer intestinal remnants and were more successfully rehabilitated and have not had complications that would lead to transplantation. Advanced intra-abdominal desmoid tumors have outcomes after resection that merit aggressive resection and planned intestinal rehabilitation and intestinal transplantation as indicated.
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Wheeler, M.; Mercer, D.; Grant, W.; Botha, J.; Langnas, A.; Thompson, J. Surgical Treatment of Intra-Abdominal Desmoid Tumors Resulting In Short Bowel Syndrome. Cancers 2012, 4, 31-38.
Wheeler M, Mercer D, Grant W, Botha J, Langnas A, Thompson J. Surgical Treatment of Intra-Abdominal Desmoid Tumors Resulting In Short Bowel Syndrome. Cancers. 2012; 4(1):31-38.
Wheeler, Matthew; Mercer, David; Grant, Wendy; Botha, Jean; Langnas, Alan; Thompson, Jon. 2012. "Surgical Treatment of Intra-Abdominal Desmoid Tumors Resulting In Short Bowel Syndrome." Cancers 4, no. 1: 31-38.