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Cancers 2011, 3(2), 2554-2596; doi:10.3390/cancers3022554
Review

State of the Art in Tumor Antigen and Biomarker Discovery

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 and *
Received: 6 April 2011; in revised form: 24 May 2011 / Accepted: 27 May 2011 / Published: 9 June 2011
(This article belongs to the Special Issue Cancer Vaccines and Immunotherapy)
View Full-Text   |   Download PDF [417 KB, uploaded 9 June 2011]
Abstract: Our knowledge of tumor immunology has resulted in multiple approaches for the treatment of cancer. However, a gap between research of new tumors markers and development of immunotherapy has been established and very few markers exist that can be used for treatment. The challenge is now to discover new targets for active and passive immunotherapy. This review aims at describing recent advances in biomarkers and tumor antigen discovery in terms of antigen nature and localization, and is highlighting the most recent approaches used for their discovery including “omics” technology.
Keywords: tumor antigen; biomarkers; immunotherapy; cancer; proteomics tumor antigen; biomarkers; immunotherapy; cancer; proteomics
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Even-Desrumeaux, K.; Baty, D.; Chames, P. State of the Art in Tumor Antigen and Biomarker Discovery. Cancers 2011, 3, 2554-2596.

AMA Style

Even-Desrumeaux K, Baty D, Chames P. State of the Art in Tumor Antigen and Biomarker Discovery. Cancers. 2011; 3(2):2554-2596.

Chicago/Turabian Style

Even-Desrumeaux, Klervi; Baty, Daniel; Chames, Patrick. 2011. "State of the Art in Tumor Antigen and Biomarker Discovery." Cancers 3, no. 2: 2554-2596.


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