Features in Microfluidic Paper-Based Devices Made by Laser Cutting: How Small Can They Be?
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Fabrication of Small-Scale Features
2.3. Test Protocols
3. Results and Discussion
3.1. Smallest Feature Size
3.2. Influence of Fiber Width on Smallest Channel Widths
3.3. Flow Behavior through Microscale Channels
3.4. Flow Behavior in Nitrocellulose Membranes
4. Conclusions
Author Contributions
Acknowledgments
Conflicts of Interest
References
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Paper Type | Smallest Channel Width (µm) |
---|---|
FP-50 | 139 ± 8 |
3MM Chr | 130 ± 11 |
1 Chr (w/o foil) | 106 ± 11 |
1 Chr | 103 ± 12 |
RC-55 | 45 ± 6 |
NC | 24 ± 3 |
1 Chr | 3MM Chr | RC-55 | |||
---|---|---|---|---|---|
Design Width (µm) | Actual Width (µm) | Design Width (µm) | Actual Width (µm) | Design Width (µm) | Actual Width (µm) |
- | - | - | - | 200 | 54 ± 3 |
300 | 210 ± 12 | 300 | 212 ± 10 | 300 | 148 ± 4 |
400 | 314 ± 8 | 400 | 298 ± 8 | 400 | 248 ± 3 |
500 | 396 ± 11 | 500 | 405 ± 7 | 500 | 341 ± 6 |
600 | 492 ± 9 | 600 | 521 ± 9 | 600 | 459 ± 5 |
800 | 699 ± 9 | 800 | 750 ± 8 | 800 | 642 ± 3 |
1100 | 973 ± 9 | 1100 | 1009 ± 9 | 1100 | 931 ± 4 |
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Mahmud, M.A.; Blondeel, E.J.M.; Kaddoura, M.; MacDonald, B.D. Features in Microfluidic Paper-Based Devices Made by Laser Cutting: How Small Can They Be? Micromachines 2018, 9, 220. https://doi.org/10.3390/mi9050220
Mahmud MA, Blondeel EJM, Kaddoura M, MacDonald BD. Features in Microfluidic Paper-Based Devices Made by Laser Cutting: How Small Can They Be? Micromachines. 2018; 9(5):220. https://doi.org/10.3390/mi9050220
Chicago/Turabian StyleMahmud, Md. Almostasim, Eric J. M. Blondeel, Moufeed Kaddoura, and Brendan D. MacDonald. 2018. "Features in Microfluidic Paper-Based Devices Made by Laser Cutting: How Small Can They Be?" Micromachines 9, no. 5: 220. https://doi.org/10.3390/mi9050220