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Micromachines 2018, 9(2), 76; doi:10.3390/mi9020076

Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation

School of Integrated Design Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan
Department of Mechanical Engineering, Keio University, Yokohama 223-8522, Japan
Author to whom correspondence should be addressed.
Received: 10 January 2018 / Revised: 3 February 2018 / Accepted: 9 February 2018 / Published: 12 February 2018
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This paper demonstrates a triple-coaxial flow device to continuously produce a hydrogel microtube using a microfluidic technique. The hydrogel microtube can encapsulate a microbial suspension, while allowing the diffusion of oxygen and nutrients into the microtube and preventing microbes from passing into or out of the microtube. The microtubes also enable the collection of the microbes after task completion without contaminating the environment. In our previous study, we used a double-coaxial flow device to produce the microtubes, but continuous production was a challenge. In the present study, we developed a microfluidic device that fabricates a triple-coaxial flow to enable continuous production of the microtubes. Here, we characterize the production capacity of the microtubes along with their properties and demonstrate bioremediation using microtubes encapsulating a microbial suspension. View Full-Text
Keywords: microtubes; triple-coaxial flow; microbes; microfluidics; bioremediation microtubes; triple-coaxial flow; microbes; microfluidics; bioremediation

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Fujimoto, K.; Higashi, K.; Onoe, H.; Miki, N. Development of a Triple-Coaxial Flow Device for Fabricating a Hydrogel Microtube and Its Application to Bioremediation. Micromachines 2018, 9, 76.

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