A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia
AbstractWe report a paper-based self-powered sensor patch for prevention and management of exercise-induced hypoglycemia. The article describes the fabrication, in vitro, and in vivo characterization of the sensor for glucose monitoring in human sweat. This wearable, non-invasive, single-use biosensor integrates a vertically stacked, paper-based glucose/oxygen enzymatic fuel cell into a standard Band-Aid adhesive patch. The paper-based device attaches directly to skin, wicks sweat by using capillary forces to a reservoir where chemical energy is converted to electrical energy, and monitors glucose without external power and sophisticated readout instruments. The device utilizes (1) a 3-D paper-based fuel cell configuration, (2) an electrically conducting microfluidic reservoir for a high anode surface area and efficient mass transfer, and (3) a direct electron transfer between glucose oxidase and anodes for enhanced electron discharge properties. The developed sensor shows a high linearity of current at 0.02–1.0 mg/mL glucose centration (R2 = 0.989) with a high sensitivity of 1.35 µA/mM. View Full-Text
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Cho, E.; Mohammadifar, M.; Choi, S. A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia. Micromachines 2017, 8, 265.
Cho E, Mohammadifar M, Choi S. A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia. Micromachines. 2017; 8(9):265.Chicago/Turabian Style
Cho, Eunyoung; Mohammadifar, Maedeh; Choi, Seokheun. 2017. "A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia." Micromachines 8, no. 9: 265.
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