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Toxins 2016, 8(12), 351; doi:10.3390/toxins8120351

Priority Actions and Progress to Substantially and Sustainably Reduce the Mortality, Morbidity and Socioeconomic Burden of Tropical Snakebite

1
Alistair Reid Venom Research Unit, Liverpool School of Tropical, Liverpool L35QA, UK
2
Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José 11501-2060, Costa Rica
*
Authors to whom correspondence should be addressed.
Academic Editor: Wolfgang Wüster
Received: 25 October 2016 / Revised: 9 November 2016 / Accepted: 18 November 2016 / Published: 24 November 2016
(This article belongs to the Section Animal Venoms)
View Full-Text   |   Download PDF [246 KB, uploaded 24 November 2016]

Abstract

The deliberations and conclusions of a Hinxton Retreat convened in September 2015, entitled “Mechanisms to reverse the public health neglect of snakebite victims” are reported. The participants recommended that the following priority actions be included in strategies to reduce the global impact of snake envenoming: (a) collection of accurate global snakebite incidence, mortality and morbidity data to underpin advocacy efforts and help design public health campaigns; (b) promotion of (i) public education prevention campaigns; (ii) transport systems to improve access to hospitals and (iii) establishment of regional antivenom-efficacy testing facilities to ensure antivenoms’ effectiveness and safety; (c) exploration of funding models for investment in the production of antivenoms to address deficiencies in some regions; (d) establishment of (i) programs for training in effective first aid, hospital management and post-treatment care of victims; (ii) a clinical network to generate treatment guidelines and (iii) a clinical trials system to improve the clinical management of snakebite; (e) development of (i) novel treatments of the systemic and local tissue-destructive effects of envenoming and (ii) affordable, simple, point-of-care snakebite diagnostic kits to improve the accuracy and rapidity of treatment; (f) devising and implementation of interventions to help the people and communities affected by physical and psychological sequelae of snakebite. View Full-Text
Keywords: snakebite; envenoming; neglected tropical disease; antivenoms; prevention; global snakebite initiative snakebite; envenoming; neglected tropical disease; antivenoms; prevention; global snakebite initiative
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Harrison, R.A.; Gutiérrez, J.M. Priority Actions and Progress to Substantially and Sustainably Reduce the Mortality, Morbidity and Socioeconomic Burden of Tropical Snakebite. Toxins 2016, 8, 351.

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