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Toxins 2015, 7(5), 1556-1615; doi:10.3390/toxins7051556

Ribosome-Inactivating and Related Proteins

Institute of Pharmacy, Freie Universitaet Berlin, Koenigin-Luise-Str. 2 + 4, 14195 Berlin, Germany
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Author to whom correspondence should be addressed.
Academic Editor: Nilgun E. Tumer
Received: 31 March 2015 / Revised: 23 April 2015 / Accepted: 28 April 2015 / Published: 8 May 2015
(This article belongs to the Special Issue Plant Toxins)
View Full-Text   |   Download PDF [1637 KB, uploaded 8 May 2015]

Abstract

Ribosome-inactivating proteins (RIPs) are toxins that act as N-glycosidases (EC 3.2.2.22). They are mainly produced by plants and classified as type 1 RIPs and type 2 RIPs. There are also RIPs and RIP related proteins that cannot be grouped into the classical type 1 and type 2 RIPs because of their different sizes, structures or functions. In addition, there is still not a uniform nomenclature or classification existing for RIPs. In this review, we give the current status of all known plant RIPs and we make a suggestion about how to unify those RIPs and RIP related proteins that cannot be classified as type 1 or type 2 RIPs. View Full-Text
Keywords: ribosome-inactivating proteins; RIPs; type 1 RIP; RIP 1; type 2 RIP; RIP 2; N-glycosidase; nomenclature of RIPs; classification of RIPs ribosome-inactivating proteins; RIPs; type 1 RIP; RIP 1; type 2 RIP; RIP 2; N-glycosidase; nomenclature of RIPs; classification of RIPs
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Schrot, J.; Weng, A.; Melzig, M.F. Ribosome-Inactivating and Related Proteins. Toxins 2015, 7, 1556-1615.

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