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Toxins 2015, 7(4), 1126-1150; doi:10.3390/toxins7041126

Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan

Chemistry and Molecular Pharmacology, Institute for Research in Biomedicine (IRB Barcelona), Baldiri i Reixac, 10, Barcelona 08028, Spain
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Authors to whom correspondence should be addressed.
Academic Editor: Sokcheon Pak
Received: 4 February 2015 / Revised: 18 March 2015 / Accepted: 25 March 2015 / Published: 1 April 2015
View Full-Text   |   Download PDF [261 KB, uploaded 1 April 2015]

Abstract

While knowledge of the composition and mode of action of bee and wasp venoms dates back 50 years, the therapeutic value of these toxins remains relatively unexploded. The properties of these venoms are now being studied with the aim to design and develop new therapeutic drugs. Far from evaluating the extensive number of monographs, journals and books related to bee and wasp venoms and the therapeutic effect of these toxins in numerous diseases, the following review focuses on the three most characterized peptides, namely melittin, apamin, and mastoparan. Here, we update information related to these compounds from the perspective of applied science and discuss their potential therapeutic and biotechnological applications in biomedicine. View Full-Text
Keywords: bee; wasp; venom; melittin; apamin; mastoparan bee; wasp; venom; melittin; apamin; mastoparan
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Moreno, M.; Giralt, E. Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan. Toxins 2015, 7, 1126-1150.

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