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Toxins 2011, 3(3), 191-200; doi:10.3390/toxins3030191

Monitoring Radiographic Brain Tumor Progression

* ,
Division of Neurosurgery, Duke University Medical Center, Box 3807, Durham, NC 27710, USA
* Author to whom correspondence should be addressed.
Received: 31 January 2011 / Revised: 3 February 2011 / Accepted: 11 March 2011 / Published: 15 March 2011
(This article belongs to the Special Issue Immunotoxins)
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Determining radiographic progression in primary malignant brain tumors has posed a significant challenge to the neuroncology community. Glioblastoma multiforme (GBM, WHO Grade IV) through its inherent heterogeneous enhancement, growth patterns, and irregular nature has been difficult to assess for progression. Our ability to detect tumor progression radiographically remains inadequate. Despite the advanced imaging techniques, detecting tumor progression continues to be a clinical challenge. Here we review the different criteria used to detect tumor progression, and highlight the inherent challenges with detection of progression.
Keywords: glioblastoma; radiographic progression; tumor progression; MRI glioblastoma; radiographic progression; tumor progression; MRI
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Mehta, A.I.; Kanaly, C.W.; Friedman, A.H.; Bigner, D.D.; Sampson, J.H. Monitoring Radiographic Brain Tumor Progression. Toxins 2011, 3, 191-200.

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