Next Article in Journal
Survey of Candidate Genes for Maize Resistance to Infection by Aspergillus flavus and/or Aflatoxin Contamination
Next Article in Special Issue
Mitigating Toxic Planktonic Cyanobacterial Blooms in Aquatic Ecosystems Facing Increasing Anthropogenic and Climatic Pressures
Previous Article in Journal
An Improved Method for the Sensitive Detection of Shiga Toxin 2 in Human Serum
Previous Article in Special Issue
Allelopathic and Bloom-Forming Picocyanobacteria in a Changing World
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessArticle
Toxins 2018, 10(2), 60; https://doi.org/10.3390/toxins10020060

Fatal Neurotoxicosis in Dogs Associated with Tychoplanktic, Anatoxin-a Producing Tychonema sp. in Mesotrophic Lake Tegel, Berlin

1
German Environment Agency, Corrensplatz 1, 14195 Berlin, Germany
2
Berlin Brandenburg State Laboratory Abt. IV, Invalidenstr. 60, 10557 Berlin, Germany
3
Nusshäherstr. 17A, 13505 Berlin, Germany
4
State Office for Health & Social Affairs (LAGeSo), Working Group Water Hygiene & Environmental Health, Postfach 31-09-29, 10639 Berlin, Germany
5
Department of Veterinary Pathology, Faculty of Veterinary Medicine, Freie Universität Berlin, Robert-von-Ostertag-Strasse 15, 14163 Berlin, Germany
6
Toxicological Laboratory, Medical University Center, 37075 Göttingen, Germany
*
Author to whom correspondence should be addressed.
Received: 22 December 2017 / Revised: 19 January 2018 / Accepted: 22 January 2018 / Published: 31 January 2018
View Full-Text   |   Download PDF [1368 KB, uploaded 31 January 2018]   |  

Abstract

In May 2017, at least 12 dogs showed signs of acute neurotoxicosis after swimming in or drinking from Lake Tegel, a mesotrophic lake in Berlin, Germany, and several of the affected dogs died shortly afterwards despite intensive veterinary treatment. Cyanobacterial blooms were not visible at the water surface or the shorelines. However, detached and floating water moss (Fontinalis antipyretica) with high amounts of Tychonema sp., a potential anatoxin-a (ATX) producing cyanobacterium, was found near the beaches where the dogs had been swimming and playing. Necropsies of two of the dogs revealed no specific lesions beside the anamnestic neurotoxicosis. ATX was detected in concentrations up to 8700 µg L−1 in the stomach contents, while other (neuro)toxic substances were not found. In the aqueous fraction of Fontinalis/Tychonema clumps sampled after the casualties, ATX was found in concentrations up to 1870 µg L−1. This is the first report of a dense population of Tychonema sp. in stands of Fontinalis resulting in high ATX contents. This case emphasizes the need for further investigation of potentially toxic, non-bloom forming cyanobacteria in less eutrophic water bodies and underlines the novel challenge of developing appropriate surveillance schemes for respective bathing sites. View Full-Text
Keywords: cyanobacteria; anatoxin-a; Tychonema; neurotoxicosis; cyanotoxins; macrophytes cyanobacteria; anatoxin-a; Tychonema; neurotoxicosis; cyanotoxins; macrophytes
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Fastner, J.; Beulker, C.; Geiser, B.; Hoffmann, A.; Kröger, R.; Teske, K.; Hoppe, J.; Mundhenk, L.; Neurath, H.; Sagebiel, D.; Chorus, I. Fatal Neurotoxicosis in Dogs Associated with Tychoplanktic, Anatoxin-a Producing Tychonema sp. in Mesotrophic Lake Tegel, Berlin. Toxins 2018, 10, 60.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Toxins EISSN 2072-6651 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top