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Toxins 2018, 10(1), 20; https://doi.org/10.3390/toxins10010020

Muscle Selection for Focal Limb Dystonia

1
Combined NeuroScience IRB, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
2
Department of Rehabilitation Medicine, National Institutes of Health, Bethesda, MD 20892, USA
*
Author to whom correspondence should be addressed.
Received: 23 October 2017 / Revised: 11 December 2017 / Accepted: 13 December 2017 / Published: 29 December 2017
(This article belongs to the Special Issue Muscle Selection for BoNT)
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Abstract

Selection of muscles for botulinum toxin injection for limb dystonia is particularly challenging. Limb dystonias vary more widely in the pattern of dystonic movement and involved muscles than cervical dystonia or blepharospasm. The large variation in how healthy individuals perform skilled hand movements, the large number of muscles in the hand and forearm, and the presence of compensatory actions in patients with dystonia add to the complexity of choosing muscles for injection. In this article, we discuss approaches to selecting upper and lower extremity muscles for chemodenervation treatment of limb dystonia. View Full-Text
Keywords: limb dystonia; writer’s cramp’ musician’s cramp; lower limb dystonia; runners dystonia; chemodenervation; botulinum toxin; muscle selection; gait testing limb dystonia; writer’s cramp’ musician’s cramp; lower limb dystonia; runners dystonia; chemodenervation; botulinum toxin; muscle selection; gait testing
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Karp, B.I.; Alter, K. Muscle Selection for Focal Limb Dystonia. Toxins 2018, 10, 20.

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