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Nutrients 2017, 9(3), 194; doi:10.3390/nu9030194

Absorption Profile of (Poly)Phenolic Compounds after Consumption of Three Food Supplements Containing 36 Different Fruits, Vegetables, and Berries

The Laboratory of Phytochemicals in Physiology, Human Nutrition Unit, Department of Food & Drug, University of Parma, 43125 Parma, Italy
Department of Food & Drug, University of Parma, 43124 Parma, Italy
Institute of Pathophysiology and Immunology, Medical University of Graz, A-8010 Graz, Austria
Division of Cardiac Surgery, Department of Surgery, Medical University of Graz, A-8010 Graz, Austria
Institute of Physiological Chemistry, Medical University of Graz, A-8010 Graz, Austria
Green Beat—Institute of Nutrient Research and Sport Nutrition, 8042 Graz, Austria
The Need for Nutrition Education/Innovation Programme (NNEdPro), Global Centre for Nutrition and Health, St John’s Innovation Centre, Cambridge CB4 0WS, UK
Author to whom correspondence should be addressed.
Received: 30 January 2017 / Revised: 21 February 2017 / Accepted: 23 February 2017 / Published: 26 February 2017
(This article belongs to the Special Issue Effects of Polyphenol-Rich Foods on Human Health)
View Full-Text   |   Download PDF [1919 KB, uploaded 26 February 2017]   |  


The market of plant-based nutraceuticals and food supplements is continuously growing due to the increased consumer demand. The introduction of new products with relevant nutritional characteristics represents a new way of providing bioactive compounds and (poly)phenols to consumers, becoming a strategy to ideally guarantee the health benefits attributed to plant foodstuffs and allowing the increase of daily bioactive compound intake. A paramount step in the study of nutraceuticals is the evaluation of the bioavailability and metabolism of their putatively active components. Therefore, the aim of the present study was to investigate the absorption profile of the (poly)phenolic compounds contained in three different plant-based food supplements, made of 36 different plant matrices, which were consumed by 20 subjects in an open one-arm study design. Blood samples were collected at baseline and 1, 2, 5, and 10 h after capsule intake. Twenty quantifiable metabolites deriving from different (poly)phenolic compounds were identified. Results showed that the consumption of the three capsules allowed the effective absorption of several (poly)phenolic compounds and metabolites appearing at different times in plasma, thereby indicating different absorption profiles. The capsules thus ensured potential health-promoting molecules to be potentially available to target tissues and organs. View Full-Text
Keywords: fruit and vegetables; capsules; (poly)phenolic compounds; absorption fruit and vegetables; capsules; (poly)phenolic compounds; absorption

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Bresciani, L.; Martini, D.; Mena, P.; Tassotti, M.; Calani, L.; Brigati, G.; Brighenti, F.; Holasek, S.; Malliga, D.-E.; Lamprecht, M.; Del Rio, D. Absorption Profile of (Poly)Phenolic Compounds after Consumption of Three Food Supplements Containing 36 Different Fruits, Vegetables, and Berries. Nutrients 2017, 9, 194.

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