Early Nutritional Interventions for Brain and Cognitive Development in Preterm Infants: A Review of the Literature
AbstractAdequate nutrition is important for neurodevelopmental outcomes in preterm‐born infants. In this review, we aim to summarize the current knowledge on nutritional interventions initiated during the hospital stay targeting brain and cognitive development benefits in preterm human infants. Studies can broadly be split in general dietary intervention studies and studies investigating specific nutrients or nutritional supplements. In general, mother’s breast milk was reported to be better for preterm infants’ neurodevelopment compared to infant formula. The differences in methodologies make it difficult to conclude any effects of interventions with individual nutrients. Only protein and iron level studies showed some consistent findings regarding optimal doses; however, confirmatory studies are needed. This review does not support some widely accepted associations, such as that between long‐chain polyunsaturated fatty acid supplementation and visual development. Clear nutritional recommendations cannot be made based on this review. However, the type of infant nutrition (i.e., breast milk versus formula or donor milk), the timing of the nutritional intervention, and the dose of the nutrient/supplement have been found to be relevant factors in determining the success of nutritional intervention studies in preterm infants. View Full-Text
- Supplementary File 1:
DOCX-Document (DOCX, 158 KB)
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Schneider, N.; Garcia‐Rodenas, C.L. Early Nutritional Interventions for Brain and Cognitive Development in Preterm Infants: A Review of the Literature. Nutrients 2017, 9, 187.
Schneider N, Garcia‐Rodenas CL. Early Nutritional Interventions for Brain and Cognitive Development in Preterm Infants: A Review of the Literature. Nutrients. 2017; 9(3):187.Chicago/Turabian Style
Schneider, Nora; Garcia‐Rodenas, Clara L. 2017. "Early Nutritional Interventions for Brain and Cognitive Development in Preterm Infants: A Review of the Literature." Nutrients 9, no. 3: 187.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.