Next Article in Journal
Early or Late Feeding after ICU Admission?
Next Article in Special Issue
Aging Gut Microbiota at the Cross-Road between Nutrition, Physical Frailty, and Sarcopenia: Is There a Gut–Muscle Axis?
Previous Article in Journal
Association between Vitamin Intake during Pregnancy and Risk of Small for Gestational Age
Previous Article in Special Issue
A Cross-Sectional Study on the Association between 24-h Urine Osmolality and Weight Status in Older Adults
Article Menu

Export Article

Open AccessArticle
Nutrients 2017, 9(12), 1276; doi:10.3390/nu9121276

Prevalence and Predictors of Subclinical Micronutrient Deficiency in German Older Adults: Results from the Population-Based KORA-Age Study

1
Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute of Epidemiology II, Ingolstädter Landtraße 1, 85764 Neuherberg, Germany
2
German Heart Centre Munich, Technical University of Munich, Lazarettstraße 36, 80636 Munich, Germany
3
DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, 80802 Munich, Germany
4
Ulm Medical Center, Department of Internal Medicine II—Cardiology, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany
5
Central Hospital of Augsburg, MONICA/KORA Myocardial Infarction Registry, Stenglinstraße 2, 86156 Augsburg, Germany
6
Institute for Medical Information Processing, Biometrics and Epidemiology, Ludwig-Maximilians-University Munich, Marchioninistraße 15, 81377 Munich, Germany
*
Author to whom correspondence should be addressed.
Received: 11 October 2017 / Revised: 16 November 2017 / Accepted: 20 November 2017 / Published: 23 November 2017
(This article belongs to the Special Issue Nutrition and Ageing)
View Full-Text   |   Download PDF [415 KB, uploaded 29 November 2017]   |  

Abstract

Subclinical micronutrient deficiency in older adults is associated with chronic age-related diseases and adverse functional outcomes. In Germany, the older population is at risk of insufficient micronutrient intake, but representative studies on micronutrient status in old and very old adults are scarce. This study’s objectives were to estimate the prevalence of subclinical vitamin D, folate, vitamin B12 and iron deficiencies among older adults, aged 65 to 93, from the KORA-Age study in Augsburg, Germany (n = 1079), and to examine associated predictors, using multiple logistic regression. Serum concentrations of 25-hydroxyvitamin D (25OHD), folate, vitamin B12, and iron were analyzed. The prevalence of subclinical vitamin D and vitamin B12 deficiencies were high, with 52.0% and 27.3% of individuals having low 25OHD (<50 nmol/L) and low vitamin B12 concentrations (<221 pmol/L), respectively. Furthermore, 11.0% had low iron (men <11.6 µmol/L, women <9.0 µmol/L) and 8.7% had low folate levels (<13.6 nmol/L). Common predictors associated with subclinical micronutrient deficiency included very old age, physical inactivity, frailty and no/irregular use of supplements. Subclinical micronutrient deficiency is a public health concern among KORA-Age participants, especially for vitamins D and B12. The predictors identified provide further rationale for screening high-risk subgroups and developing targeted public health interventions to tackle prevailing micronutrient inadequacies among older adults. View Full-Text
Keywords: subclinical micronutrient deficiency; vitamin D; folate; vitamin B12; iron; predictors; older adults; population-based study; Germany subclinical micronutrient deficiency; vitamin D; folate; vitamin B12; iron; predictors; older adults; population-based study; Germany
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Conzade, R.; Koenig, W.; Heier, M.; Schneider, A.; Grill, E.; Peters, A.; Thorand, B. Prevalence and Predictors of Subclinical Micronutrient Deficiency in German Older Adults: Results from the Population-Based KORA-Age Study. Nutrients 2017, 9, 1276.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top