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Nutrients 2017, 9(1), 70; doi:10.3390/nu9010070

Phytomedicine in Joint Disorders

1
Medical Semiology Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania
2
Nephrology Clinic, University Emergency Hospital Bucharest, 050098 Bucharest, Romania
3
Biochemistry Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania
4
Physiology Department, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, B-dul “Eroilor Sanitari” nr. 8, Sector 6, 76241 Bucharest, Romania
5
R&D IRIST LABMED SRL, Str. Miraslau, nr. 24, Sector 3, 031235 Bucharest, Romania
6
Orthopaedic and Trauma Clinic 2, Faculty of General Medicine, “Carol Davila” University of Medicine and Pharmacy, 020022 Bucharest, Romania
7
Clinical Emergency Hospital Bucharest, 014461 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Received: 12 December 2016 / Revised: 11 January 2017 / Accepted: 12 January 2017 / Published: 16 January 2017
(This article belongs to the Special Issue Dietary Bioactives and Bone Health)
View Full-Text   |   Download PDF [273 KB, uploaded 16 January 2017]   |  

Abstract

Chronic joint inflammatory disorders such as osteoarthritis and rheumatoid arthritis have in common an upsurge of inflammation, and oxidative stress, resulting in progressive histological alterations and disabling symptoms. Currently used conventional medication (ranging from pain-killers to biological agents) is potent, but frequently associated with serious, even life-threatening side effects. Used for millennia in traditional herbalism, medicinal plants are a promising alternative, with lower rate of adverse events and efficiency frequently comparable with that of conventional drugs. Nevertheless, their mechanism of action is in many cases elusive and/or uncertain. Even though many of them have been proven effective in studies done in vitro or on animal models, there is a scarcity of human clinical evidence. The purpose of this review is to summarize the available scientific information on the following joint-friendly medicinal plants, which have been tested in human studies: Arnica montana, Boswellia spp., Curcuma spp., Equisetum arvense, Harpagophytum procumbens, Salix spp., Sesamum indicum, Symphytum officinalis, Zingiber officinalis, Panax notoginseng, and Whitania somnifera. View Full-Text
Keywords: osteoarthritis; rheumatoid arthritis; medicinal plants; herbs osteoarthritis; rheumatoid arthritis; medicinal plants; herbs
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Dragos, D.; Gilca, M.; Gaman, L.; Vlad, A.; Iosif, L.; Stoian, I.; Lupescu, O. Phytomedicine in Joint Disorders. Nutrients 2017, 9, 70.

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