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Nutrients 2016, 8(2), 90; doi:10.3390/nu8020090

Myricetin: A Dietary Molecule with Diverse Biological Activities

1
Department of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria 0001, South Africa
2
SAMRC Herbal Drugs Research Unit, Faculty of Science, Tshwane University of Technology, Pretoria 0001, South Africa
*
Author to whom correspondence should be addressed.
Received: 9 November 2015 / Revised: 16 December 2015 / Accepted: 23 December 2015 / Published: 16 February 2016
(This article belongs to the Special Issue Flavonoids, Inflammation and Immune System)
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Abstract

Myricetin is a common plant-derived flavonoid and is well recognised for its nutraceuticals value. It is one of the key ingredients of various foods and beverages. The compound exhibits a wide range of activities that include strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities. It displays several activities that are related to the central nervous system and numerous studies have suggested that the compound may be beneficial to protect against diseases such as Parkinson’s and Alzheimer’s. The use of myricetin as a preserving agent to extend the shelf life of foods containing oils and fats is attributed to the compound’s ability to protect lipids against oxidation. A detailed search of existing literature revealed that there is currently no comprehensive review available on this important molecule. Hence, the present work includes the history, synthesis, pharmaceutical applications and toxicity studies of myricetin. This report also highlights structure-activity relationships and mechanisms of action for various biological activities. View Full-Text
Keywords: myricetin; anti-oxidant activity; anti-HIV activity; cytotoxicity; polyphenol; anti-alzheimer activity myricetin; anti-oxidant activity; anti-HIV activity; cytotoxicity; polyphenol; anti-alzheimer activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Semwal, D.K.; Semwal, R.B.; Combrinck, S.; Viljoen, A. Myricetin: A Dietary Molecule with Diverse Biological Activities. Nutrients 2016, 8, 90.

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