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Nutrients 2016, 8(11), 685; doi:10.3390/nu8110685

Early Life Fructose Exposure and Its Implications for Long-Term Cardiometabolic Health in Offspring

1
Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Diabetes Research Center of Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
2
Department of Pediatrics, The Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
*
Author to whom correspondence should be addressed.
Received: 17 September 2016 / Revised: 8 October 2016 / Accepted: 24 October 2016 / Published: 1 November 2016
View Full-Text   |   Download PDF [447 KB, uploaded 1 November 2016]   |  

Abstract

It has become increasingly clear that maternal nutrition can strongly influence the susceptibility of adult offspring to cardiometabolic disease. For decades, it has been thought that excessive intake of fructose, such as sugar-sweetened beverages and foods, has been linked to increased risk of obesity, type 2 diabetes, and cardiovascular disease in various populations. These deleterious effects of excess fructose consumption in adults are well researched, but limited data are available on the long-term effects of high fructose exposure during gestation, lactation, and infancy. This review aims to examine the evidence linking early life fructose exposure during critical periods of development and its implications for long-term cardiometabolic health in offspring. View Full-Text
Keywords: early life; fructose; sugar-sweetened beverages; cardiometabolic health; offspring early life; fructose; sugar-sweetened beverages; cardiometabolic health; offspring
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Zheng, J.; Feng, Q.; Zhang, Q.; Wang, T.; Xiao, X. Early Life Fructose Exposure and Its Implications for Long-Term Cardiometabolic Health in Offspring. Nutrients 2016, 8, 685.

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