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Nutrients 2015, 7(11), 9185-9217; doi:10.3390/nu7115460

The Role of Maternal Dietary Proteins in Development of Metabolic Syndrome in Offspring

Department of Nutrition and Dietetics, Brook College of Health, University of North Florida, UNF Dr. Bldg 39, Room 3057A, Jacksonville, FL 32224, USA
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Received: 31 August 2015 / Revised: 16 October 2015 / Accepted: 28 October 2015 / Published: 6 November 2015
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Abstract

The prevalence of metabolic syndrome and obesity has been increasing. Pre-natal environment has been suggested as a factor influencing the risk of metabolic syndrome in adulthood. Both observational and experimental studies showed that maternal diet is a major modifier of the development of regulatory systems in the offspring in utero and post-natally. Both protein content and source in maternal diet influence pre- and early post-natal development. High and low protein dams’ diets have detrimental effect on body weight, blood pressure191 and metabolic and intake regulatory systems in the offspring. Moreover, the role of the source of protein in a nutritionally adequate maternal diet in programming of food intake regulatory system, body weight, glucose metabolism and blood pressure in offspring is studied. However, underlying mechanisms are still elusive. The purpose of this review is to examine the current literature related to the role of proteins in maternal diets in development of characteristics of the metabolic syndrome in offspring. View Full-Text
Keywords: protein; fetal programming; metabolic syndrome protein; fetal programming; metabolic syndrome
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Jahan-Mihan, A.; Rodriguez, J.; Christie, C.; Sadeghi, M.; Zerbe, T. The Role of Maternal Dietary Proteins in Development of Metabolic Syndrome in Offspring. Nutrients 2015, 7, 9185-9217.

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