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Nutrients 2014, 6(4), 1635-1648; doi:10.3390/nu6041635
Article

Intake of Tibetan Hull-Less Barley is Associated with a Reduced Risk of Metabolic Related Syndrome in Rats Fed High-Fat-Sucrose Diets

1,†
, 2,†
 and 1,*
1 Department of Food Science and Nutrition, College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China 2 Department of Neurology, Huashan Hospital, Jingan 200040, Shanghai, China These authors contributed equally to this work and should be considered co-first authors.
* Author to whom correspondence should be addressed.
Received: 30 December 2013 / Revised: 2 April 2014 / Accepted: 2 April 2014 / Published: 21 April 2014
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Abstract

The objective of this study was to assess the effects of whole grain Tibetan hull-less barley on metabolic related syndrome induced by high-fat-sucrose diets in rats. The diets were designed to reflect the dietary patterns of Chinese individuals (>30% energy fat) with refined wheat flour (HFS-W) or Tibetan hull-less barley (HFS-THB) as the main carbohydrate sources. Rats fed HFS-W had increased body weight, abdominal fat deposition, liver weight, liver fat deposition, triglyceride (TG), fasting blood glucose (FBG), serum fasting insulin (FINS), and homeostasis model assessment of insulin resistance (HOMA-IR) scores, and decreased low-density lipoprotein cholesterol (LDL-C) levels compared to rats fed a basal diet (BD). However, rats fed HFS-THB had reduced body weight gain, dyslipidemia, and insulin resistance. These findings indicate that whole Tibetan hull-less barley is a functional food that can reduce the prevalence of metabolic related syndrome induced by high-fat-sucrose diets.
Keywords: Tibetan hull-less barley (THB); whole grain; metabolic related syndrome; insulin resistance Tibetan hull-less barley (THB); whole grain; metabolic related syndrome; insulin resistance
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Gong, L.; Gong, L.; Zhang, Y. Intake of Tibetan Hull-Less Barley is Associated with a Reduced Risk of Metabolic Related Syndrome in Rats Fed High-Fat-Sucrose Diets. Nutrients 2014, 6, 1635-1648.

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