The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD)

doi:10.3390/nu4121828

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Nutrients 2012, 4(12), 1828-1850; doi:10.3390/nu4121828

Review

The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD)

Melissa I. Chang, Mark Puder and Kathleen M. Gura*

Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02215, USA

* Author to whom correspondence should be addressed.

Received: 30 October 2012; in revised form: 11 November 2012 / Accepted: 19 November 2012 / Published: 27 November 2012

(This article belongs to the Special Issue Parenteral Nutrition)

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Abstract: Since 2004, fish oil based lipid emulsions have been used in the treatment of intestinal failure associated liver disease, with a noticeable impact on decreasing the incidence of morbidity and mortality of this often fatal condition. With this new therapy, however, different approaches have emerged as well as concerns about potential risks with using fish oil as a monotherapy. This review will discuss the experience to date with this lipid emulsion along with the rational for its use, controversies and concerns.

Keywords: parenteral nutrition; pediatrics; lipid emulsions; intestinal failure-related liver disease; fish oil

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Cite This Article

MDPI and ACS Style

Chang, M.I.; Puder, M.; Gura, K.M. The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD). Nutrients 2012, 4, 1828-1850.

AMA Style

Chang MI, Puder M, Gura KM. The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD). Nutrients. 2012; 4(12):1828-1850.

Chicago/Turabian Style

Chang, Melissa I.; Puder, Mark; Gura, Kathleen M. 2012. "The Use of Fish Oil Lipid Emulsion in the Treatment of Intestinal Failure Associated Liver Disease (IFALD)." Nutrients 4, no. 12: 1828-1850.

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