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Serum Fatty Acid Reference Ranges: Percentiles from a New Zealand National Nutrition Survey
Department of Human Nutrition, University of Otago, Dunedin 9054, New Zealand
Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
Faculty of Land and Food Systems, the University of British Columbia, Vancouver, British Columbia, Canada
Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford OX3 7lJ, UK
* Author to whom correspondence should be addressed.
Received: 26 November 2010; in revised form: 29 December 2010 / Accepted: 4 January 2011 / Published: 20 January 2011
Abstract: Serum fatty acids are increasingly used in cross-sectional surveys and cohort studies as biomarkers of dietary fat intake; however, it is currently difficult to judge whether an individual has low or high fatty acid status, or whether the distribution of fatty acids of a group of people is low or high due to a lack of appropriate reference values. In the absence of interpretive criteria, the distribution of serum fatty acids from a suitable reference population can be used as an alternative. We describe the distribution of the fatty acid composition of the three most commonly reported lipid classes in serum; cholesterol ester, phospholipid and triacylgycerol. Results for each serum lipid class are presented as means (SD) and percentiles (5, 10, 25, 50, 75, 90, and 95) of serum fatty acids in non-fasting blood samples collected from a population based cross-sectional survey of New Zealand adults (n = 2793). These serum fatty acid reference ranges are applicable and relevant to Australia, United Kingdom, and United States as well as other countries where fat intakes are similar to New Zealand.
Keywords: serum fatty acids; nutrition surveys; reference ranges; biomarkers
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Bradbury, K.E.; Skeaff, C.M.; Crowe, F.L.; Green, T.J.; Hodson, L. Serum Fatty Acid Reference Ranges: Percentiles from a New Zealand National Nutrition Survey. Nutrients 2011, 3, 152-163.
Bradbury KE, Skeaff CM, Crowe FL, Green TJ, Hodson L. Serum Fatty Acid Reference Ranges: Percentiles from a New Zealand National Nutrition Survey. Nutrients. 2011; 3(1):152-163.
Bradbury, Kathryn E.; Skeaff, Clark Murray; Crowe, Francesca L.; Green, Timothy J.; Hodson, Leanne. 2011. "Serum Fatty Acid Reference Ranges: Percentiles from a New Zealand National Nutrition Survey." Nutrients 3, no. 1: 152-163.