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Nutrients 2018, 10(7), 834; https://doi.org/10.3390/nu10070834

Therapeutic Role of Green Tea Polyphenols in Improving Fertility: A Review

1
College of Animal Science and Technology, Anhui Agricultural University, 130 West Changjiang Road, Hefei 230036, China
2
Anhui Provincial Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding, Anhui Agricultural University, 130 West Changjiang Road, Hefei 230036, China
*
Author to whom correspondence should be addressed.
Received: 13 May 2018 / Revised: 23 June 2018 / Accepted: 23 June 2018 / Published: 27 June 2018
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Abstract

Sperm cells are highly sensitive to reactive oxygen species (ROS), which are produced during cellular oxidation. In normal cell biology, ROS levels increase with a decreasing antioxidant response, resulting in oxidative stress which threatens sperm biology. Oxidative stress has numerous effects, including increased apoptosis, reduced motion parameters, and reduced sperm integrity. In this regard, green tea polyphenols (GrTPs) have been reported to possess properties that may increase the quality of male and female gametes, mostly via the capability of catechins to reduce ROS production. GrTPs have antioxidant properties that improve major semen parameters, such as sperm concentration, motility, morphology, DNA damage, fertility rate, and gamete quality. These unique properties of green tea catechins could improve reproductive health and represent an important study area. This exploratory review discusses the therapeutic effects of GrTPs against infertility, their possible mechanisms of action, and recommended supportive therapy for improving fertility in humans and in animals. View Full-Text
Keywords: oxidative stress; green tea polyphenol; antioxidant; fertility; supportive therapy oxidative stress; green tea polyphenol; antioxidant; fertility; supportive therapy
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Rahman, S.U.; Huang, Y.; Zhu, L.; Feng, S.; Khan, I.M.; Wu, J.; Li, Y.; Wang, X. Therapeutic Role of Green Tea Polyphenols in Improving Fertility: A Review. Nutrients 2018, 10, 834.

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