Next Article in Journal
Guanidinoacetic Acid and Creatine are Associated with Cardiometabolic Risk Factors in Healthy Men and Women: A Cross-Sectional Study
Previous Article in Journal
Validation of a Rapid Method to Assess Habitual Beverage Intake Patterns
Article Menu
Issue 1 (January) cover image

Export Article

Open AccessArticle
Nutrients 2018, 10(1), 85; https://doi.org/10.3390/nu10010085

Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans

1
Brain, Performance and Nutrition Research Centre, Northumbria University, Newcastle Upon-Tyne NE1 8ST, UK
2
innoVactiv Inc., Rimouski, QC G5L 9H3, Canada
3
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON M4G 4J6, Canada
*
Author to whom correspondence should be addressed.
Received: 3 November 2017 / Revised: 6 December 2017 / Accepted: 10 January 2018 / Published: 13 January 2018
View Full-Text   |   Download PDF [867 KB, uploaded 13 January 2018]   |  

Abstract

(Poly)phenols and, specifically, phlorotannins present in brown seaweeds have previously been shown to inhibit α-amylase and α-glucosidase, key enzymes involved in the breakdown and intestinal absorption of carbohydrates. Related to this are observations of modulation of post-prandial glycemic response in mice and increased insulin sensitivity in humans when supplemented with seaweed extract. However, no studies to date have explored the effect of seaweed extract on cognition. The current randomized, placebo-controlled, double-blind, parallel groups study examined the impact of a brown seaweed extract on cognitive function post-prandially in 60 healthy adults (N = 30 per group). Computerized measures of episodic memory, attention and subjective state were completed at baseline and 5 times at 40 min intervals over a 3 h period following lunch, with either seaweed or placebo consumed 30 min prior to lunch. Analysis was conducted with linear mixed models controlling for baseline. Seaweed led to significant improvements to accuracy on digit vigilance (p = 0.035) and choice reaction time (p = 0.043) tasks. These findings provide the first evidence for modulation of cognition with seaweed extract. In order to explore the mechanism underlying these effects, future research should examine effects on cognition in parallel with blood glucose and insulin responses. View Full-Text
Keywords: seaweed; cognition; cognitive; mood; phlorotannin; phenolic; polyphenol; phytochemical seaweed; cognition; cognitive; mood; phlorotannin; phenolic; polyphenol; phytochemical
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Haskell-Ramsay, C.F.; Jackson, P.A.; Dodd, F.L.; Forster, J.S.; Bérubé, J.; Levinton, C.; Kennedy, D.O. Acute Post-Prandial Cognitive Effects of Brown Seaweed Extract in Humans. Nutrients 2018, 10, 85.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top