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Pharmaceutics 2016, 8(2), 11; doi:10.3390/pharmaceutics8020011

Turning Waste into Value: Nanosized Natural Plant Materials of Solanum incanum L. and Pterocarpus erinaceus Poir with Promising Antimicrobial Activities

1
Division of Bioorganic Chemistry, School of Pharmacy, Saarland University, Saarbruecken D-66123, Germany
2
Department of Biotechnology, University of Applied Sciences, Kaiserslautern, Zweibruecken 66482, Germany
3
Laboratoire de Botanique et Ecologie Végétale, Université de Lomé, BP 1515 Lomé, Togo
4
CNRS (Centre National de la Recherche Scientifique), SRSMC (Structure et Réactivité des Systèmes Moléculaires Complexes) UMR 7565, 1 boulevard Arago, Metz F57070, France
5
Université de Lorraine, SRSMC, UMR 7565, Nancy Cedex F-54001, France
6
Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University-Medical College, ul. Medyczna 9, Cracow 30-688, Poland
7
ABC Platform, Faculté de Pharmacie, Nancy Cedex F-54001, France
8
Department of Pharmacognosy, Faculty of Clinical Pharmacy, Al Baha University, Al Baha 15791, Saudi Arabia
9
Institute of Pharmaceutics and Biopharmaceutics, Philipps-Universität Marburg, Marburg 35032, Germany
*
Authors to whom correspondence should be addressed.
Academic Editor: Leena Peltonen
Received: 2 February 2016 / Revised: 20 March 2016 / Accepted: 23 March 2016 / Published: 19 April 2016
(This article belongs to the Special Issue Nanocrystals)
View Full-Text   |   Download PDF [7354 KB, uploaded 19 April 2016]   |  

Abstract

Numerous plants are known to exhibit considerable biological activities in the fields of medicine and agriculture, yet access to their active ingredients is often complicated, cumbersome and expensive. As a consequence, many plants harbouring potential drugs or green phyto-protectants go largely unnoticed, especially in poorer countries which, at the same time, are in desperate need of antimicrobial agents. As in the case of plants such as the Jericho tomato, Solanum incanum, and the common African tree Pterocarpus erinaceus, nanosizing of original plant materials may provide an interesting alternative to extensive extraction and isolation procedures. Indeed, it is straightforward to obtain considerable amounts of such common, often weed-like plants, and to mill the dried material to more or less uniform particles of microscopic and nanoscopic size. These particles exhibit activity against Steinernema feltiae or Escherichia coli, which is comparable to the ones seen for processed extracts of the same, respective plants. As S. feltiae is used as a model nematode indicative of possible phyto-protective uses in the agricultural arena, these findings also showcase the potential of nanosizing of crude “waste” plant materials for specific practical applications, especially—but not exclusively—in developing countries lacking a more sophisticated industrial infrastructure. View Full-Text
Keywords: nanosizing; antimicrobial activity; phyto-protectant; Pterocarpus erinaceus; Solanum incanum nanosizing; antimicrobial activity; phyto-protectant; Pterocarpus erinaceus; Solanum incanum
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Griffin, S.; Tittikpina, N.K.; Al-marby, A.; Alkhayer, R.; Denezhkin, P.; Witek, K.; Gbogbo, K.A.; Batawila, K.; Duval, R.E.; Nasim, M.J.; Awadh-Ali, N.A.; Kirsch, G.; Chaimbault, P.; Schäfer, K.-H.; Keck, C.M.; Handzlik, J.; Jacob, C. Turning Waste into Value: Nanosized Natural Plant Materials of Solanum incanum L. and Pterocarpus erinaceus Poir with Promising Antimicrobial Activities. Pharmaceutics 2016, 8, 11.

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