Control of Hepatitis B Virus by Cytokines
AbstractHepatitis B virus (HBV) infection remains a major public health problem worldwide with more than 240 million individuals chronically infected. Current treatments can control HBV replication to a large extent, but cannot eliminate HBV infection. Cytokines have been shown to control HBV replication and contribute to HBV cure in different models. Cytokines play an important role in limiting acute HBV infection in patients and mediate a non-cytolytic clearance of the virus. In this review, we summarize the effects of cytokines and cytokine-induced cellular signaling pathways on different steps of the HBV life cycle, and discuss possible strategies that may contribute to the eradication of HBV through innate immune activation. View Full-Text
Share & Cite This Article
Xia, Y.; Protzer, U. Control of Hepatitis B Virus by Cytokines. Viruses 2017, 9, 18.
Xia Y, Protzer U. Control of Hepatitis B Virus by Cytokines. Viruses. 2017; 9(1):18.Chicago/Turabian Style
Xia, Yuchen; Protzer, Ulrike. 2017. "Control of Hepatitis B Virus by Cytokines." Viruses 9, no. 1: 18.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.