A Current Overview of the Papaya meleira virus, an Unusual Plant Virus
AbstractPapaya meleira virus (PMeV) is the causal agent of papaya sticky disease, which is characterized by a spontaneous exudation of fluid and aqueous latex from the papaya fruit and leaves. The latex oxidizes after atmospheric exposure, resulting in a sticky feature on the fruit from which the name of the disease originates. PMeV is an isometric virus particle with a double-stranded RNA (dsRNA) genome of approximately 12 Kb. Unusual for a plant virus, PMeV particles are localized on and linked to the polymers present in the latex. The ability of the PMeV to inhabit such a hostile environment demonstrates an intriguing interaction of the virus with the papaya. A hypersensitivity response is triggered against PMeV infection, and there is a reduction in the proteolytic activity of papaya latex during sticky disease. In papaya leaf tissues, stress responsive proteins, mostly calreticulin and proteasome-related proteins, are up regulated and proteins related to metabolism are down-regulated. Additionally, PMeV modifies the transcription of several miRNAs involved in the modulation of genes related to the ubiquitin-proteasome system. Until now, no PMeV resistant papaya genotype has been identified and roguing is the only viral control strategy available. However, a single inoculation of papaya plants with PMeV dsRNA delayed the progress of viral infection. View Full-Text
Share & Cite This Article
Abreu, P.M.V.; Antunes, T.F.S.; Magaña-Álvarez, A.; Pérez-Brito, D.; Tapia-Tussell, R.; Ventura, J.A.; Fernandes, A.A.R.; Fernandes, P.M.B. A Current Overview of the Papaya meleira virus, an Unusual Plant Virus. Viruses 2015, 7, 1853-1870.
Abreu PMV, Antunes TFS, Magaña-Álvarez A, Pérez-Brito D, Tapia-Tussell R, Ventura JA, Fernandes AAR, Fernandes PMB. A Current Overview of the Papaya meleira virus, an Unusual Plant Virus. Viruses. 2015; 7(4):1853-1870.Chicago/Turabian Style
Abreu, Paolla M.V.; Antunes, Tathiana F.S.; Magaña-Álvarez, Anuar; Pérez-Brito, Daisy; Tapia-Tussell, Raúl; Ventura, José A.; Fernandes, Antonio A.R.; Fernandes, Patricia M.B. 2015. "A Current Overview of the Papaya meleira virus, an Unusual Plant Virus." Viruses 7, no. 4: 1853-1870.