Viruses 2014, 6(8), 3311-3333; doi:10.3390/v6083311
Review

Immunogenetics of Small Ruminant Lentiviral Infections

1
, 2
 and 1,*
Received: 23 May 2014; in revised form: 18 August 2014 / Accepted: 19 August 2014 / Published: 22 August 2014
(This article belongs to the Special Issue Small Ruminant Lentiviruses)
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Abstract: The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similarities with the human immunodeficiency virus (HIV), HIV research can shed light on the possible immune mechanisms that control or lead to disease progression. This review will focus on the host immune response to HIV-1 and SRLV, and will discuss the possibility of breeding for enhanced SRLV disease resistance.
Keywords: SRLV; immune response; genetic selection
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Stonos, N.; Wootton, S.K.; Karrow, N. Immunogenetics of Small Ruminant Lentiviral Infections. Viruses 2014, 6, 3311-3333.

AMA Style

Stonos N, Wootton SK, Karrow N. Immunogenetics of Small Ruminant Lentiviral Infections. Viruses. 2014; 6(8):3311-3333.

Chicago/Turabian Style

Stonos, Nancy; Wootton, Sarah K.; Karrow, Niel. 2014. "Immunogenetics of Small Ruminant Lentiviral Infections." Viruses 6, no. 8: 3311-3333.


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