Next Article in Journal
Role of Virus-Encoded microRNAs in Avian Viral Diseases
Next Article in Special Issue
A Role for CD81 and Hepatitis C Virus in Hepatoma Mobility
Previous Article in Journal
HCMV Infection of Human Trophoblast Progenitor Cells of the Placenta Is Neutralized by a Human Monoclonal Antibody to Glycoprotein B and Not by Antibodies to the Pentamer Complex
Previous Article in Special Issue
Evidence Showing that Tetraspanins Inhibit HIV-1-Induced Cell-Cell Fusion at a Post-Hemifusion Stage
Viruses 2014, 6(3), 1365-1378; doi:10.3390/v6031365
Review

Super-Resolution Microscopy: A Virus’ Eye View of the Cell

Institute of Immunity and Transplantation, University College London, London NW3 2PF, UK
Received: 13 January 2014 / Revised: 1 March 2014 / Accepted: 11 March 2014 / Published: 19 March 2014
(This article belongs to the Special Issue Viruses and Tetraspanins)
View Full-Text   |   Download PDF [688 KB, uploaded 12 May 2015]   |  

Abstract

It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and cell biology. This article provides an introduction to super-resolution imaging; in particular, localisation microscopy, and explores the application of such technologies to the study of viruses and tetraspanins, the topic of this special issue.
Keywords: microscopy; super-resolution; PALM; STORM; dSTORM; tetraspanin; virus assembly; virus entry microscopy; super-resolution; PALM; STORM; dSTORM; tetraspanin; virus assembly; virus entry
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Grove, J. Super-Resolution Microscopy: A Virus’ Eye View of the Cell. Viruses 2014, 6, 1365-1378.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert