Next Article in Journal
HCMV Reprogramming of Infected Monocyte Survival and Differentiation: A Goldilocks Phenomenon
Previous Article in Journal
Identification by Mass Spectrometry and Immune Response Analysis of Guinea Pig Cytomegalovirus (GPCMV) Pentameric Complex Proteins GP129, 131 and 133
Article Menu

Export Article

Open AccessReview
Viruses 2014, 6(2), 752-781; doi:10.3390/v6020752

Experimental Infections of Wild Birds with West Nile Virus

Centro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Valdeolmos (Madrid), 28130, Spain
*
Author to whom correspondence should be addressed.
Received: 2 December 2013 / Revised: 4 February 2014 / Accepted: 4 February 2014 / Published: 13 February 2014
(This article belongs to the Section Animal Viruses)
View Full-Text   |   Download PDF [935 KB, uploaded 12 May 2015]   |  

Abstract

Avian models of West Nile virus (WNV) disease have become pivotal in the study of infection pathogenesis and transmission, despite the intrinsic constraints that represents this type of experimental research that needs to be conducted in biosecurity level 3 (BSL3) facilities. This review summarizes the main achievements of WNV experimental research carried out in wild birds, highlighting advantages and limitations of this model. Viral and host factors that determine the infection outcome are analyzed in detail, as well as recent discoveries about avian immunity, viral transmission, and persistence achieved through experimental research. Studies of laboratory infections in the natural host will help to understand variations in susceptibility and reservoir competence among bird species, as well as in the epidemiological patterns found in different affected areas. View Full-Text
Keywords: West Nile virus; wild birds; experimental infection; pathogenesis; transmission; immunity; host competence West Nile virus; wild birds; experimental infection; pathogenesis; transmission; immunity; host competence
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Pérez-Ramírez, E.; Llorente, F.; Jiménez-Clavero, M.Á. Experimental Infections of Wild Birds with West Nile Virus. Viruses 2014, 6, 752-781.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top